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News articleYahoo Finance· January 21, 2026

Johnson & Johnson reports Q4 and Full-Year 2025 results

View original at finance.yahoo.com
Johnson & Johnson reports Q4 and Full-Year 2025 results 2025 Fourth-Quarter reported sales growth of 9.1% to $24.6 Billion with operational growth of 7.1%* and adjusted operational growth of 6.1%*; 2025 Fourth-Quarter earnings per share (EPS) of $2.10 and adjusted EPS of $2.46, both include $(0.10) due to the acquisiti…
Opening lines of the source · Yahoo Finance · short snapshot — read the full document at the original

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  • 2026 adjusted operational EPS guidance of $11.28-$11.48 with midpoint of $11.38 representing 5.5% growth

    80% confidence
  • 2026 adjusted EPS guidance of $11.43-$11.63 with midpoint of $11.53 representing 6.9% growth

    80% confidence
  • TREMFYA is the only IL-23 inhibitor proven to inhibit structural joint damage in active psoriatic arthritis

    80% confidence
  • INLEXZO achieved 74% disease-free survival at one year in BCG-unresponsive high-risk papillary-only NMIBC

    80% confidence
  • DARZALEX FASPRO is the first/only FDA-approved treatment for high-risk smoldering multiple myeloma

    80% confidence
  • 2026 adjusted operational sales growth guidance of 5.4%-6.4% with midpoint of 5.9%

    80% confidence
  • RYBREVANT FASPRO + LAZCLUZE has the shortest administration time for first-line combination regimen

    80% confidence
  • 2026 operational sales guidance of $99.5B-$100.5B with midpoint of $100.0B representing 6.2% growth

    80% confidence
  • TECVAYLI + DARZALEX FASPRO demonstrated superior PFS and OS vs. standard of care in second-line multiple myeloma

    80% confidence
  • Nipocalimab is the first/only investigational FcRn blocker showing potential to reduce SLE activity in Phase 2

    80% confidence
  • AKEEGA demonstrates 54% reduction in disease progression in BRCA2-mutated metastatic castration-sensitive prostate cancer

    80% confidence
  • 2026 reported sales guidance of $100.0B-$101.0B with midpoint of $100.5B representing 6.7% growth

    80% confidence
  • Subcutaneous amivantamab achieved 45% overall response rate with 7.2-month median duration in recurrent/metastatic head and neck cancer

    80% confidence

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ESMO 2026 Oncology Catalyst Cluster: Ivonescimab's PDUFA Date and Small-Cap Biotech Delistings
ESMO 2026 (Oct 22-24) concentrates a wave of oncology readouts. Summit's ivonescimab (10 presentations, positive HARMONi-GI1 OS, new EA2251 Phase II/III with ECOG-ACRIN) leads, ahead of its FDA PDUFA date of 2026-11-14, and Daiichi Sankyo's DXd ADC platform (REJOICE-Ovarian, DESTINY-Lung04, TUXEDO-3) follows. At the other end of the capital-markets spectrum, micro-cap Spago Nanomedical is moving to delist from Nasdaq First North (board resolution Oct 22, EGM Nov 19, application Jan 2027). Pivotal data and regulatory milestones are rewarding well-funded late-stage players, while cash-constrained early-stage developers are exiting public markets.
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EPKINLY Regulatory-Clinical Success Cascade
High probability of expanded label indications, additional combination approvals, and competitive positioning strength in follicular lymphoma market. Predicts positive commercial uptake and potential accelerated review for related indications.
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Where sources disagree
Ford Motor Company
Both facts give cash for Ford Motor Company at the same point in time (2025-12-31; FY 2025 year-end and Q4 2025 year-end are the same date). Both are labelled USD, but the values are 23,356,000,000 and 23.356, which cannot both be true in USD. The two numbers agree once the second is read as billions (23.356 bn = 23,356,000,000), so the economic content is consistent and the conflict is a unit/scale error in the Q4 2025 record. The period is not the reason for the conflict: a Q4 and an FY figure at the same year-end date should match.
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